产品货号：
Z39038
中文名称：
USP2抗体
英文名称：
Anti-USP2 Antibody (Clone#1738CT331.50.87)
产品规格：
50μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-USP2 Antibody (Clone#1738CT331.50.87) |
| 指标别名 | Deubiquitinating enzyme 2;ubiquitin specific peptidase 2;Ubiquitin thiolesterase 2;UBP41;USP2;USP9 |
| 克隆性 | Monoclonal |
| 检验物种 | human,African green monkey |
| 应用范围 | WB |
| 基因名称 | USP2 |
| 克隆号 | 1738CT331.50.87 |
| 抗体来源 | Mouse |
| 免疫原 | This USP2 antibody is generated from a mouse immunized with a recombinant protein between 1-258 amino acids from human USP2. |
| 计算分子量 | 68kDa |
| 成分 | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| 纯化方式 | This antibody is purified through a protein G column,followed by dialysis against PBS |
| 保存条件 | Maintain refrigerated at 2～8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
| 背景资料 | Hydrolase that deubiquitinates polyubiquitinated target proteins such as MDM2,MDM4 and CCND1.Isoform 1 and isoform 4 possess both ubiquitin-specific peptidase and isopeptidase activities.Deubiquitinates MDM2 without reversing MDM2-mediated p53/TP53 ubiquitination and thus indirectly promotes p53/TP53 degradation and limits p53 activity.Has no deubiquitinase activity against p53/TP53.Prevents MDM2-mediated degradation of MDM4.Plays a role in the G1/S cell-cycle progression in normal and cancer cells.Plays a role in the regulation of myogenic differentiation of embryonic muscle cells.Regulates the circadian clock by modulating its intrinsic circadian rhythm and its capacity to respond to external cues.Associates with clock proteins and deubiquitinates core clock component PER1 but does not affect its overall stability.Regulates the nucleocytoplasmic shuttling and nuclear retention of PER1 and its repressive role on the clock transcription factors CLOCK and ARNTL/BMAL1 (By similarity). |
| Uniprot ID | O75604 |
相关搜索：USP2抗体，USP2单抗，Anti-USP2 Antibody (Clone#1738CT331.50.87)